German-American Bank Building, Historic bank building in St. Joseph, United States.

The German-American Bank Building is a six-story bank building in St. Joseph featuring rectangular brick construction that blends Richardsonian Romanesque and Beaux-Arts styles. The facade displays carved columns and handcrafted details that give the structure a solid, confident appearance.

The building opened in 1889 and changed its name to American National Bank in 1918. This shift reflected broader social changes during World War I, when institutions with German ties rebranded themselves.

The bank was founded to serve the region's large German-speaking population, and its name kept that link until 1918, when it became American National Bank. The building later housed First Federal Savings and Loan. In 2014 Legal Aid of Western Missouri and several other businesses occupied it.

Legal Aid of Western Missouri and several other businesses occupied the building when the 2014 renovation was announced. That two-year, $20 million project by Heartland Health and Mosaic Life Care was to fit out office space for up to 200 health workers, keeping the natural brick walls and carved columns.

In 1986 the Historic American Buildings Survey photographed and documented parts of the building, leaving a measured record of its brickwork and carved columns. The building sits within St. Joseph's Commerce and Banking Historic District, listed on the National Register in 1978.