Desert Biosphere Reserve, Biosphere reserve in Pine Valley, Utah, United States.

Desert Biosphere Reserve is a protected research area in Utah's arid landscape containing diverse habitats with sagebrush shrubland and pinyon-juniper woodlands across multiple elevation zones. The varied terrain and soil types allow scientists to study how dry ecosystems function under different conditions.

The site was established as an experimental research station in 1933 and received UNESCO recognition as a biosphere reserve in 1976. This designation ended in 2017, though scientific work at the location continued.

The reserve's name comes from the Desert Range Experiment Station, and grazing and range research has shaped the land since 1933. Shadscale saltbush and sagebrush cover the benchlands, with single-leaf pinyon and juniper woodland on the higher ground of the Tunnel Springs Mountains. Visitors see a working Great Basin shrub-steppe landscape rather than a park.

Visitors should prepare for the dry environment with adequate water and clothing for changing temperatures. Exploration outside marked trails is restricted to protect research activities and vegetation.

The reserve lies about 40 miles west of Milford, and its northern section covers the southern half of the Tunnel Springs Mountains. It was named a UNESCO biosphere reserve in 1976, but that status was withdrawn on 14 June 2017. The U.S. Forest Service's Rocky Mountain Research Station still maintains the range.