L'Antiquaille, History museum in 5th arrondissement, Lyon, France.

L'Antiquaille is a history museum housed in a former hospital building and documents the spread of Christianity in ancient Gaul. The structure contains multiple exhibition levels, including underground chambers that reveal how early Christians lived and worshipped in this region.

The Antiquaille hospital closed in 2003, and the ECCLY association was founded on the initiative of Emmanuel Payen, former rector of Fourvière, and senator Jacques Moulinier to open an interpretation centre on the Christian origins of Gaul. The space opened in December 2014 in the former hospital, directed by Pierre Tricou. In 2005 the mosaic crypt and the presumed cell of Saint Pothin were listed as Monuments Historiques.

The exhibits feature paintings and mosaics that show how early Christian communities grew in the Lyon area. These works help visitors understand the role that this region played in spreading Christianity across ancient Gaul.

The site is at 49 montée Saint-Barthélemy on the Fourvière hill, a short walk from the Lugdunum museum and the Gallo-Roman theatres. The mosaic crypt and the presumed cell of Saint Pothin, both listed as Monuments Historiques since 2005, are reached underground, so allow time for the stairs and the low, enclosed spaces.

The crypt adjoining the presumed cell of Saint Pothin holds mosaics made between 1877 and 1893 by Ennemond Mora and Ange Minala, restored by workshops from Saint-Romain-en-Gal and Marseille. The stone pillar at its centre lists names such as Albina, Potamius Episc, Zacharias Presb and Aemilia, recalling the martyrs of 177.