Chiesa della Santissima Trinità, Romanesque church in Brindisi, Italy.

The church of the Santissima Trinità, also called Santa Lucia, stands in Brindisi's historic centre with a gabled facade. Inside, three naves are divided by arches built between the 15th and 16th centuries, with side altars added at the same time. The crypt, dating to the early 13th century, is divided into three naves on four columns with Corinthian capitals.

A female monastery of penitent nuns, the "bianche" of the Order of Santa Maria di Valleverde from Acri, was attached to the church and is documented in 1248; the settlement probably dates to the time of Frederick II. Between the 15th and 16th centuries the church was modified with arches dividing the three naves and side altars were added. No trace of the cloister remains.

The church remains a living place of worship where the local community gathers for religious celebrations and daily prayer. Residents connect with centuries of spiritual practice through the rituals and gatherings that continue within its walls.

The church is accessible on foot through the historic center of Brindisi, located among narrow streets and traditional squares. Visiting during quieter times of day offers a more peaceful experience for exploring the interior.

In the crypt, begun in the early 13th century, four columns with Corinthian capitals divide three naves; among its frescoes are a Saint Nicholas, a Saint Blaise, a Mary Magdalene, a Saint Peter the Apostle and a Virgin Kyriotissa showing eastern influence.