Saint John the Baptist Church, Eastern Orthodox cathedral in Cathedral Square, Kargopol, Russia.

Saint John the Baptist Church is a white stone Orthodox church on Cathedral Square, built in 1740–1752. At 35 metres it is Kargopol's tallest building, with three tiers of windows: round-arched below, octagonal above. Its four-pitched roof carries five widely spaced drums with double baroque domes, the only such doubled cupolas in the city.

Built between 1740 and 1752 on Sobornaya Square, the church replaced an earlier wooden parish church standing to the left of the Christ Nativity Cathedral. In 1994 it joined the Kargopol Historical, Architectural and Art Museum-Reserve, and in 1996 it was handed to the Archangel and Kholmogory Diocese. Since 2017 it has belonged to the Plessetsk Diocese.

The parish maintains prayer rooms in Nyandoma's special boarding school for juvenile offenders and in Kargopol's home for the elderly and disabled, and runs a Sunday school for children. The rector is Archpriest Andrei (Usachyov), with Priest Mikhail (Buzynkin) as cleric. A large icon of the Kargopol wonderworkers was kept here.

The church stands on Sobornaya Square, immediately left of the Christ Nativity Cathedral, and is the tallest building in Kargopol at 35 metres. The exterior is in good condition, but the interior is bare: the iconostasis is only marked by paper icons on plywood boards. Sunday children's catechism classes are held here.

The church is the only one in Kargopol with double domes: each of the four small baroque drums carries a second, smaller onion dome above the lower one, a device recalling local wooden churches. Its three-tiered windows also differ by level, with rounded arches below and octagonal openings at the top.