One-Million-Liter Test Sphere

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One-Million-Liter Test Sphere, Biological warfare test facility in Frederick, Maryland, US

The steel sphere reaches four stories in height, with a 40-foot diameter and one-inch-thick walls designed for containing biological experiments.

From 1951 to 1969, this structure served as the primary biological warfare research chamber at Fort Detrick under the U.S. Army Biological Warfare Laboratories.

Operation Whitecoat utilized this facility to conduct research with over 2,300 Army volunteers, contributing to the development of vaccines against various diseases.

The sphere maintains a negative pressure system ensuring containment of tested materials, with multiple access ports positioned around its circumference for specimen handling.

The structure survived a 1974 fire that destroyed its surrounding building and remains the largest aerobiology chamber ever constructed in the United States.

Location: Maryland

GPS coordinates: 39.43430,-77.42900

Latest update: May 25, 2025 00:44

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