DEPO2015, Entertainment centre in Jižní Předměstí, Plzeň, Czech Republic.

DEPO2015 is a cultural center housed in a converted transportation depot in Plzen, featuring exhibition galleries, performance venues, and workshop spaces. The complex spans the original bus and trolleybus facility with multiple distinct areas each adapted for different types of activities and events.

The building originally served as an operating depot for buses and trolleybuses, functioning as essential transportation infrastructure for the city for decades. It was converted in 2015 when Plzen became the European Capital of Culture, giving the facility its new cultural purpose.

The site's name comes from its former role as a tram depot, and the annual BLIK BLIK light festival, first held in 2015, uses the grounds for installations by Czech and foreign artists. The Tržnice DEPO market, opened in 2018, hosted themed weekend markets such as Dožínky and Masopust before closing for reconstruction in 2024.

DEPO2015 occupies the former transport depot on Presslova Street in Plzeň's Jižní Předměstí district. The grounds hold several separate buildings, so allow time to move between the halls, courtyard and garden. The Tržnice market hall and its café Ústředna have been closed for reconstruction since 2024; the café Foyer by the large Autobusová hala hall opened in early 2025.

The site's first building was a sugar factory erected in the late 1860s under the sugar specialist Hugo Jelínek; it closed after poor beet harvests and a crash of securities on the Vienna stock exchange. The tram depot that followed was built under the inventor František Křižík with the Škoda works, and the 1930s workshop building is credited to Josef Farkač, Hanuš Zápala, Stanislav Smola and František Mlynařík.