Knoxville Veterans Administration Hospital Historic District, Veterans medical complex in Knoxville, Iowa.

The Knoxville Veterans Administration Hospital Historic District occupies a 345-acre site that held five brick structures, a greenhouse and several frame buildings when the government bought it in 1922. Buildings 1-5, 8-9, the warehouse, engineering shops, power plant, four resident quarters, three garages, the VA flag pole and a dairy barn went up in 1923; Buildings 101 and 102 followed in 1944.

The site began in 1892 as an Institute for the Blind, then shifted to serve returning soldiers after World War I. This transformation reflects how existing buildings were repurposed to meet the growing need for veteran care.

The site's name changed with each use: State Industrial Home for the Blind from 1892, State Hospital for Inebriates two years after it closed in 1900, then a temporary veterans hospital in 1920. Local citizens protested the inebriates hospital, and it closed a few years later. The city of Knoxville advocated for a permanent veterans facility, secured the following year.

The campus covers 345 acres (140 ha) and held five brick structures, a greenhouse and several frame buildings when the government bought it in 1922. Buildings 1-5, 8-9, the warehouse, engineering shops, power plant, four resident quarters, three garages, the flag pole and a dairy barn went up in 1923; Buildings 101 and 102 followed in 1944. The fire station, laundry and education building were renovated in 1996.

The cemetery holds 40 plots and occupies the middle of the former VA golf course, making it the first part of the property to be developed. It predates the hospital buildings that later surrounded it.