Jardín Botánico de Santa Cruz de la Sierra, Botanical garden in Santa Cruz de la Sierra, Bolivia.

The Jardín Botánico de Santa Cruz de la Sierra covers 217 hectares at kilometre 8.5 of the Santa Cruz–Cotoca road in the Guapilo area, at 375 m elevation. The Guapilo stream divides it into a subtropical forest of tall trees with dense crowns, a Chaco forest of thorny trees and cacti, and a transition forest between them. About 6 km of interpretive trails cross the grounds.

Noel Kempff Mercado, a Bolivian professor, created the garden on 25 September 1985 to conserve plants of Bolivia's aquatic ecosystems and of the Santa Cruz de la Sierra region. The French Wikipedia gives 1984 as the founding year. The garden later joined the Association of Botanical Gardens of Latin America and the Caribbean, with the institutional code SCRUZ.

The garden displays the diversity of local plant life and how the forests of the region naturally connect. Visitors can see how different plant species live together and why this matters for the Santa Cruz area.

Visitors can walk several kilometers of trails through different forest areas and observe wildlife and plants along the way. There are seating areas and grilling facilities available if you want to spend time relaxing or having a picnic.

The garden's international botanical institution code is SCRUZ, and it belongs to the Association of Botanical Gardens of Latin America and the Caribbean. Its 217 hectares are crossed by the Guapilo stream, a tributary of the Piraí river, whose water flows eastward and divides the collections into two sections.