20th Century Club, Neoclassical clubhouse in Reno, United States.

The 20th Century Building at 335 West First Street in Reno is the former clubhouse of the Twentieth Century Club, completed in 1925 by builders Roush and Belz. Architect Fred M. Schadler combined Classical Revival and Prairie School elements in its design. It was listed on the National Register of Historic Places on April 21, 1983.

The Twentieth Century Club was organized in 1894 with 84 women and Mrs. Walter McNab Miller as first president. Members started a circulating library that year and funded a University of Nevada scholarship in 1898. In 1901 they helped found the Kindergarten Association and pressed for public kindergartens statewide. The club sold its 1925 Fred M. Schadler-designed clubhouse in 1980.

The club's name, chosen in 1894, looked ahead to the coming 20th century. The building hosted weddings, luncheons, dinner dances and civic meetings; the club sold it in 1980 and gave its Steinway grand piano to the Reno Philharmonic. The club still meets monthly from September through May for luncheons with music or guest speakers.

The former clubhouse at 335 West First Street was sold in 1980 and is now a private building, so visits are limited to its exterior. The Twentieth Century Club itself still meets monthly from September through May for luncheons with music or guest speakers, though it no longer owns a building in Reno.

The organization distributes approximately twenty thousand dollars annually to local charitable organizations and awards medical career scholarships for female students. This continued financial support demonstrates the club's enduring commitment to the community since its founding.