Meise Botanic Garden, Botanical garden and research center in Meise, Belgium

Meise Botanic Garden covers 92 hectares across Meise and Wemmel, holding about 18,000 species. Its Plant Palace in Wemmel is a one-hectare glasshouse complex: thirteen large greenhouses, 8 to 16 metres high, around twenty-two smaller collection houses, finished in 1958. The grounds take in the Bouchout Castle estate and what remains of the Meise Castle estate, whose orangery survives. The Amelvonnebeek runs through the site.

The garden grew out of the garden of the former Nassau Palace in Brussels, where the École centrale was set up in 1797. In 1826 it became the botanical garden of Saint-Josse-ten-Noode; in 1870 the Belgian state bought it and the collections expanded. The move to the 92-hectare Bouchout estate in Meise and Wemmel began in 1958 and was completed in the 1970s. On 1 January 2014 the federal garden passed to the Flemish Region and took the name Meise Botanic Garden.

The garden's name changed with its transfer from the Belgian federal state to the Flemish Region on 1 January 2014, when it became Plantentuin Meise. Its scientific journal, Plant Ecology and Evolution, launched in 2010 and is run with the Royal Belgian Botanical Society. The Emiel Van Rompaey prize, funded by a bequest from his sister Irma, is awarded every two years for floristic research.

The garden straddles Meise and Wemmel, about ten kilometres from central Brussels. The Plant Palace greenhouses, finished in 1958, cover one hectare and range from 8 to 16 metres high; thirteen large houses surround twenty-two smaller collection houses. The Balat greenhouse of 1854, moved here from Brussels, stands near the Bouchout park with the herb garden and conifer collection beside it.

The seed bank keeps wild-plant seeds in freezers at -20 °C, including 211 wild bean species, the largest such collection in the world. The garden also holds two Wollemia nobilis, a conifer known from 90-million-year-old fossils until living trees were found in Australia in 1994; scientists were taken to the site blindfolded to keep it secret.