Protestant St. Mary's Church, Weissenfels, Parish church in Weißenfels, Germany.

St. Marien is a late Gothic hall church on the Weißenfels market square, its choir closing the square to the east with a five-sided polygonal apse of rough grey and brown stone, tall traceried windows and dark buttresses. The pale yellow west tower carries a dark onion dome and spire; the nave and choir are under steep grey roofs with a pointed spire.

First mentioned in 1158 as the market settlement's church, it was consecrated in 1351. The Hussites destroyed the medieval building in 1430; the late Gothic choir was begun first, and the five-bay nave followed from 1455/56. The tower received its hipped roof between 1530 and 1535, and after the 1718 town fire a pilastered baroque top was added in 1718–1722.

The pulpit, made between 1673 and 1674 by Andreas Griebenstein with painters Christian Hoffmann and Johann Christoph Goldner, carries high reliefs of the Saviour and the four Evangelists on its sandstone basket. The stair balustrade shows the Good Shepherd and a mirrored view of Weißenfels before the 1718 town fire. The painted gallery parapets depict Old and New Testament scenes.

The church stands on the market square, its choir facing the square and the tower set back along Marienkirchgasse. The main entrance is through the pointed-arch portals on the north and south sides of the nave. Inside, the side-aisle galleries and the west gallery frame the view toward the choir.

The Ladegast organ has 41 stops on three manuals and a pedal. Eule Orgelbau of Bautzen restored it from 2018 to 2021 and returned it to its original stoplist. The church also holds a small four-stop organ that Eule built in 1953 and placed in the south aisle.