San Girolamo, Catholic church in Cannaregio, Venice, Italy.

San Girolamo is a church in the Cannaregio sestiere, along the rio de San Girolamo. The present building is a reconstruction by Domenico Rossi from the early 18th century, with interior decoration by Francesco Zugno. Inside, on the right wall, hangs Palma il Giovane's painting of Saint Jerome.

Augustinian nuns from Murano, fleeing the Hungarian troops of King Lajos, founded a convent with a small oratory here in 1375; the convent was enlarged and a church built during the same century, completed in 1425. Damaged by fire in 1456, the buildings were rebuilt, then destroyed again by a fire in 1705. Domenico Rossi rebuilt the present church in the early 18th century, reconsecrated on 15 June 1751; the French suppressed church and convent in 1807, and the building was restored and reopened in 1952.

The church houses religious artworks and altarpieces that have held meaning for local worshippers over centuries. The main altar made from Carrara marble with bronze decorations forms the spiritual center of the space.

The church stands along the rio de San Girolamo in Cannaregio, so it is reached on foot or by boat rather than by road. It was restored and reopened in 1952 and is again used for worship. Look for the entrance on the canal side; the bell tower was demolished after becoming unsafe, so the roofline is lower than in older views.

The church is where Blessed Peter of Pisa (1355–1435), founder of the Congregation of the Poor Hermits of Saint Jerome, is buried. The bell tower was once turned into a factory chimney and later demolished because it was unsafe.