Riserva naturale orientata Isola di Lampedusa, Nature reserve in Lampedusa, Italy

Riserva naturale orientata Isola di Lampedusa is a regional nature reserve of 369.68 hectares on Lampedusa, the largest of the Pelagie Islands, between the Vallone dell'Acqua to the west and Cala Greca to the east. It also takes in the Isola dei Conigli. The island is made of limestone deposits from the Middle to Upper Miocene, and the reserve is managed by Legambiente Sicilia.

The Sicilian Region established the reserve with decrees 291/44 of 16 May 1995 and 533/44 of 11 August 1995, covering 369.68 hectares between the Vallone dell'Acqua and Cala Greca, including the Isola dei Conigli. Management was assigned to Legambiente Sicilia. The island's original Mediterranean scrub had been largely cleared under Bourbon colonisation to create farmland for settlers.

The name of the reserve refers directly to the island itself, which has long sat at a crossing point between Europe and Africa. Walking along the protected coast today, visitors notice how the vegetation, rock colors, and sea shades look different from other parts of Italy.

The reserve covers 369.68 hectares between the Vallone dell'Acqua to the west and Cala Greca to the east, and includes the Isola dei Conigli. It is managed by Legambiente Sicilia under the Sicilian regional department for territory and environment. Access is on foot along the island's paths; the Isola dei Conigli is reached by wading a shallow channel.

The Isola dei Conigli, a small islet inside the reserve, is the only Italian site of the Algerian sand lizard (Psammodromus algirus), and its beach is where about one hundred pairs of yellow-legged gulls nest. The islet also holds the reserve's only known Italian station of the hooded snake (Macroprotodon cucullatus).