San Siro Church, Catholic church in Lomazzo, Italy.

San Siro Church sits on Via Milano with a neoclassical facade designed by architect Federico Frigerio in the early 20th century. The building houses multiple altars and vaulted ceilings with artistic decorations throughout its interior spaces.

The church was founded over 1500 years ago and originally marked the boundary between Milan and Como territories. Its current neoclassical structure dates to the early 20th century, replacing earlier buildings at this historically significant location.

The church keeps the relics of the martyr Epiphanius, moved here in the 17th century from the Roman catacombs and placed in a gilded wooden case under the main altar. On the nave vault, the patrons of the former dependent communities face each other: Saint Bartholomew for Manera and Saint Remigius for Caslino al Piano.

The church stands on the Como side of Lomazzo, the historic diocesan border that split the town between Como and Milan until 1974. The facade by Federico Frigerio faces the street; its tympanum pinnacles copy those on Como Cathedral's dome. The interior is a single very long nave, lengthened in the 19th century, so allow time to walk its full length.

In the 17th century the church was entrusted with the relics of the martyr Epiphanius, moved from the Roman catacombs: bones, inscription and a small flask of earth soaked with his blood, kept in a gilded wooden case beneath the high altar.