Fort Defiance, Plantation house in Caldwell County, North Carolina, United States

Fort Defiance is a two-story frame plantation house near Lenoir in Caldwell County, North Carolina. Its main block, measuring 28 by 40 feet, was built between 1788 and 1792, and a wing was added in 1823. It was the home of Revolutionary War General William Lenoir.

Fort Defiance takes its name from a stockade built on the Yadkin River in summer 1776 by troops under Elijah Isaacs, then called Fort Isaacs. The frame plantation house was raised between 1788 and 1792 for Revolutionary War General William Lenoir, with a wing added in 1823. The Caldwell County Historical Society acquired the property in 1965, and it joined the National Register of Historic Places in 1970.

Fort Defiance takes its name from the earlier Fort Isaacs, the 1776 camp of Elijah Isaacs's troops on the Yadkin River. The house was the home of General William Lenoir, and in 1842 politician George Washington Hayes married his second wife here. The Caldwell County Historical Society has run it as a historic house museum since 1965.

The house stands near Lenoir, off the Yadkin River in Caldwell County, and is operated as a historic house museum by the Caldwell County Historical Society, which received the property in 1965. The main block is a two-story frame structure of 28 by 40 feet, with a wing added in 1823; allow time to walk the grounds and the interior rooms.

The house stands on the site of Fort Isaacs, a 1776 encampment of troops under Elijah Isaacs on the Yadkin River. Western North Carolina politician George Washington Hayes married his second wife there on February 6, 1842. The Caldwell County Historical Society took over the property in 1965.