Nicholas Building, Office building in Toledo, United States

The Nicholas Building is a 17-story, 250-foot office tower at 608 Madison Avenue in Downtown Toledo. It was designed by Norval Bacon and Thomas Huber of Bacon & Huber and completed in 1906 for cousins A.L. and C.M. Spitzer, who named it after their grandfather Nicholas Spitzer.

The building was constructed in 1906 and reflects the Commercial Palazzo architectural style. This period marked a turning point in urban development when such office and commercial structures shaped the city center.

The building is named after Nicholas Spitzer, grandfather of the cousins A.L. and C.M. Spitzer who built it in 1906. From 1954 the National Bank of Toledo occupied it, and after the bank's 1989 acquisition Fifth Third Bank remained the main tenant until moving to One SeaGate in 2007.

The Nicholas Building stands at 608 Madison Avenue in Downtown Toledo, a short walk from the Toledo-Lucas County Public Library. It is an office tower rather than a public attraction, so visits are limited to the lobby and street-level views of the facade. The building is currently Toledo's seventh-tallest at 250 ft.

The Nicholas Building was described in 1910 as one of the "largest and most modern office buildings in the Northwest", a region then covering today's East North Central States. It remained Toledo's tallest building for seven years, from 1906 until the Riverfront Apartments was completed in 1913, and is now the city's seventh-tallest at 250 ft.