Liceo N° 35 Instituto Alfredo Vásquez Acevedo, Secondary education center in Montevideo, Uruguay.

Liceo N° 35 Instituto Alfredo Vásquez Acevedo is a secondary school housed in an art nouveau building on José Enrique Rodó Street in central Montevideo. The structure features ornamental elements typical of this architectural style, with distinct decorative details throughout its interior and exterior.

Secondary education was organised as a section of the University of the Republic in 1880 on the proposal of Alfredo Vásquez Acevedo. The 1903 award of the block between 18 de Julio, Eduardo Acevedo, José Enrique Rodó and Emilio Frugoni streets allowed the 1911 inauguration of the building by Alfredo Jones Brown, with 1,871 pupils enrolled. A girls' section opened in 1913 under Clotilde Luisi; in 1935 secondary teaching left the university and the institute took its present name, and in 1940 it became baccalaureate-only.

The school's name honours Alfredo Vásquez Acevedo, the jurist and politician who in 1868 co-founded the Sociedad de Amigos de la Educación Popular with José Pedro Varela and Elbio Fernández. In 1913 a separate female secondary section opened here under Clotilde Luisi. In the assembly hall Juana de Ibarbourou, Gabriela Mistral and Alfonsina Storni met once, all three together.

The building can be viewed and photographed from the street due to its protected monument status. The facade is best appreciated from José Enrique Rodó Street, where you can see the architectural details clearly.

The school building was declared a National Historical Monument in 1976 and underwent major restoration work between 2004 and 2009. During this restoration, many original architectural elements were carefully preserved and brought back to their original condition.