Centennial Museum and Chihuahuan Desert Gardens, Botanical garden at University of Texas, El Paso, United States.

Centennial Museum and Chihuahuan Desert Gardens is a botanical garden at the university displaying more than 600 native plant species from the region's desert environment. The indoor museum sections hold 70,000 objects, ranging from prehistoric remains to items from the twentieth century.

The museum opened in 1936 to mark Texas' centennial and was the first museum established in the city. Its creation coincided with the university's early development as an institution.

The museum's cultural exhibits cover the indigenous, colonial, pre-urban and folk cultures of the border regions of the southwestern United States and Mexico. Its collection of Casas Grandes pottery from northern Mexico is displayed in the galleries and on the museum's website. The gardens hold more than 600 species of plants native to the Greater Chihuahuan Desert, arranged in a series of theme gardens.

The museum is open Monday through Saturday, 10:00 am to 4:00 pm, and closed on university holidays and UTEP home football game days. Admission is free, with special-needs access and limited parking; parking fees apply. Tours must be booked in advance. The gardens lie on the UTEP campus beside the university parking lot at 500 W. University Avenue.

The gardens' website hosts transcripts of more than 1,300 short radio pieces on Southwestern subjects first aired by the local NPR station, KTEP, alongside online courses such as An Introduction to the Chihuahuan Desert. The gardens are a member of Botanic Gardens Conservation International.