Jardín botánico de la Universidad de Caldas, Botanical garden at University of Caldas in Manizales, Colombia.

The Botanical Garden of the University of Caldas is a botanical garden and arboretum in Manizales, Colombia, managed by the university. Its international botanical institution code and herbarium acronym is MANI. The garden holds collections of native Andean forest trees, medicinal plants, ornamental plants, and crop plants, including the wax palm (Ceroxylon quindiuense), Colombia's national tree.

The garden began in 1960 under the administration of the University of Caldas in Manizales, and its herbarium carries the international code MANI. From the outset its work has centred on the situation and use of plant resources in the Department of Caldas, organised around three lines: ethnobotany, plants at risk of extinction, and strategies for preserving forest and jungle areas, with emphasis on water production and soil protection.

The garden's ethnobotany programme studies plants used locally for crafts, medicine and food, supporting rural communities in Caldas. Among the native trees on display are the arrayán de Manizales (Lafoensia speciosa), declared the city's emblem tree by municipal agreement in 1990, and the wax palm (Ceroxylon quindiuense), Colombia's national tree.

The grounds are accessible on weekdays from 8 to 17 hours and on weekends from 9 to 17 hours, allowing visitors to explore all sections of the site. Since the garden sits at mountain elevation, a jacket is advisable, and pathways may vary in condition depending on weather.

The institution focuses on three main research areas: ethnobotany, protection of endangered plant species, and preservation of strategic forest areas in the Caldas region. This specialized work sets it apart from typical display gardens and makes it an active research center.