Port of Tampa, Maritime port in Tampa Bay, United States.

Port Tampa Bay, known as the Port of Tampa until January 2014, occupies parts of Tampa Bay, Hillsborough Bay, McKay Bay, Old Tampa Bay and the mouth of the Hillsborough River, about 25 sea miles from the Gulf of Mexico. It handles container ships, tankers, roll-on/roll-off vessels and cruise ships, with three cruise terminals and ship repair facilities.

The port's origins trace back to Fort Brooke, established in 1824 as the settlement that would anchor the region's growth. Major dock construction and infrastructure development followed in the early twentieth century, transforming the area into a significant commercial hub.

Five cruise lines homeport here: Carnival, Royal Caribbean, Holland America, Margaritaville at Sea and Norwegian; AIDA calls in. Nearby stand Channelside, The Florida Aquarium and Ybor City, one of Florida's two National Historic Districts. The port also runs Foreign Trade Zone #79, serving importers along the I-4 corridor.

The cruise terminals and port headquarters line Channelside Drive, with the Lee Roy Selmon Expressway running along the port's northern edge; its elevated reversible lanes link Meridian Avenue, three blocks west of the cruise terminal, to Interstate 75. The Interstate 4–Selmon Expressway Connector, opened in 2013, carries trucks on 1.1 miles of exclusive lanes so they bypass Ybor City's streets. Nearby are Channelside, The Florida Aquarium and Ybor City.

Álvar Núñez Cabeza de Vaca, a leader of the Narváez expedition, anchored in Tampa Bay on April 12, 1528, and described it as "the best in the world" for naval and maritime commerce. The port district also holds Foreign Trade Zone #79, which helps companies along the I-4 Corridor with importing, exporting and distribution.