First Baptist Church, Protestant church in Panama City, United States.

First Baptist Church is a Protestant house of worship in Panama City featuring classical architectural design with a prominent steeple. The building displays a balanced facade along North Main Street and incorporates traditional religious architectural details.

First Baptist Church began in 1908 with F. H. Poston as its first pastor; before that, Panama City residents of several denominations worshipped together in a one-room schoolhouse. Pastor W. A. Burns moved the congregation from its first site to a more stately location between 1926 and 1929. E. D. McDaniel, pastor from July 1931 to May 1949, began recording the church's history.

The church began in 1908 with F. H. Poston as first pastor, and early residents of Panama City had worshipped in a one-room schoolhouse shared with other denominations. E. D. McDaniel recorded the congregation's history during his pastorate from July 1931 to May 1949. The church later bought the town's old National Guard Armory and renovated it as the Family Life Building.

The congregation moved sites over the decades and used several sanctuaries; the original 1908 building was still in use in 2008. An educational building was added in the 1950s, and the former National Guard armory was renovated as the Family Life Building. Check current service times before visiting.

The congregation bought the town's old National Guard Armory and renovated it into a Family Life Building, and in the 1950s it put up a separate educational building. The original church building was still in use as of 2008, after several sanctuaries had served the congregation over the years.