San Francisco Federal Building, Deconstructivist skyscraper in San Francisco, United States.

The San Francisco Federal Building is an 18-story skyscraper with angular metallic panels and glass surfaces creating geometric patterns across its exterior. The facade design makes the building's structure visible and gives it a distinctive character when you look at it.

Construction began in 2003 and the building opened in 2007, later than planned, at a cost of $144 million. Morphosis won the commission through a GSA brief that required energy efficiency, and the design omitted a conventional HVAC system, saving $11 million. In 2023 the Consolidated Appropriations Act named it after Speaker Nancy Pelosi.

The building is named after Nancy Pelosi, Speaker of the House, under the Consolidated Appropriations Act of 2023; its formal name remains San Francisco Federal Building. Employees use elevators that stop only every third floor and walk one flight of stairs, a design Thom Mayne intended to promote health and interaction. Critics have called the tower provocative, and in 2020 an executive order named it an unsatisfactory federal design.

The building occupies the corner of Mission and 7th streets in South of Market; it is a working federal office tower, not a sight open to visitors, so the interior offices and plaza-level areas are not for touring. Its ventilation relies on sensor-controlled windows and a south wall of perforated stainless steel panels that draws cooler air upward, so conditions inside shift with the weather. The four-story annex and the shaded ground-level plaza can be seen from the street.

The building's windows open and close automatically based on outside temperature, which reduces cooling and heating costs. This system runs throughout the day and continuously adjusts to changing weather conditions.