Lui Seng Chun, Grade I historic building in Mong Kok, Hong Kong.

Lui Seng Chun is a four-story shophouse at the intersection of Lai Chi Kok and Tong Mi Roads in Mong Kok, featuring curved facades, granite columns, and decorative balustrades. The structure combines traditional Chinese and Western architectural elements throughout its design.

Lui Leung, a founder of Kowloon Motor Bus, bought the Lai Chi Kok Road site in 1929 and commissioned architect W. H. Bourne; the building was completed in 1931. Its ground floor housed the Lui Seng Chun bone-setting medicine shop, while the upper floors were family residences. The shop closed a few years after Lui's death in 1942, and the building later served as tailor shops and housing before being donated to the government in 2000. It reopened in 2012 as a Chinese medicine clinic.

The name comes from a couplet meaning Lui's medicine could bring a patient back to life. The ground-floor shop sold bone-setting medicinal wine, popular locally and overseas. Since 2012 the ground floor has sold herbal tea made to Baptist University formulas, and the former shop plaques are back in place.

The building now operates as a Chinese medicine healthcare center managed by Hong Kong Baptist University and sits at a busy intersection with good access. The location is easy to reach on foot and surrounded by other shops and local amenities.

The 2016 film Doctor Strange used a replica of Lui Seng Chun as the Hong Kong sanctum of the Masters of the Mystic Arts. The building's curved corner and balconies stood in for the fictional headquarters, linking the 1931 shophouse to a global film audience.