Chiesa di Santa Maria Madre della Misericordia, Catholic church in Prenestino-Labicano district, Rome, Italy.

Santa Maria Madre della Misericordia is a church on Via dei Gordiani in Rome's Prenestino-Labicano district, designed by Tullio Rossi in the mid-20th century. Its facade takes the form of a hut with a tiled roof and a projecting porch. Inside, the plan is a long rectangle with a ceiling of wooden trusses, and the walls hold no works of art.

The church began as a vice-curacy in 1937, carved out of the parish of Santi Marcellino e Pietro ad Duas Lauros. Cardinal Vicar Clemente Micara erected it as a parish on 15 July 1952, first entrusting it to the Poor Servants of Divine Providence founded by Don Calabria, then to the diocesan clergy. Pope John Paul II visited on 1 May 1983.

The name refers to Mary as Mother of Mercy, the title under which the church is dedicated. The parish was first run by the Poor Servants of Divine Providence, the congregation founded by Don Calabria in Verona, before passing to the secular clergy of the Diocese of Rome. Pope John Paul II visited the parish on 1 May 1983.

The church stands on Via dei Gordiani in the Prenestino-Labicano district, east of the city centre. The entrance is through the projecting porch beneath the hut-shaped, tiled facade. Inside, the single rectangular hall with its wooden truss ceiling can be taken in at a glance from the door.

The interior is entirely bare of artworks, so nothing distracts from the wooden truss ceiling and the hut-shaped facade with its tiled roof and projecting porch. The church was a vice-parish from 1937, became a parish on 15 July 1952, and was visited by Pope John Paul II on 1 May 1983.