Palazzo Michiel del Brusà, Gothic palace on Grand Canal, Cannaregio, Italy.

Palazzo Michiel del Brusà rises from the Grand Canal in Cannaregio with a symmetrical facade of pale stone and stucco in three levels. Two water portals with dark green panels open at the base; above, two noble floors carry quadriforas with three-lobe Gothic flowers on each arch, flanked by pairs of single lancet windows with projecting balconies. A red tile roof with a small central dormer tops the attic mezzanine. Inside, stucco and frescoes are largely by Jacopo Guarana.

A devastating fire in 1774 caused by a maid's accident destroyed much of the building's interior, but the original facade survived the flames. The palace was carefully restored between 1777 and the following years, preserving the Gothic front while rebuilding what lay behind it.

The name Michiel belonged to one of Venice's noble families, which gave the republic three doges, among them Domenico Michiel (1117–1130) and Vitale II Michiel (1156–1172), both forced to abdicate. The Venetian word brusà, "burned", recalls the 1774 fire started by a maid's neglect. A Latin inscription on the facade records the city-funded rebuilding of 1777.

The palace stands between Palazzo Michiel dalle Colonne and Palazzo Smith Mangilli Valmarana, with its main front on the Grand Canal and a second ground-level portal opening onto the Strada Nova. It is owned by the Global Art Affairs Foundation, so access depends on the exhibitions and events it hosts there. Approaching on foot along the Strada Nova shows the landward entrance; the water side is seen from the canal.

Three members of the Michiel family who lived here served as Doge of Venice, with two of them being forced to give up their power. This unusual political history tied to the palace makes the building a window into the complex struggles between powerful families that shaped Venice.