Holy Trinity Church in Chelyabinsk, Eastern Orthodox church building in Chelyabinsk, Russia

Holy Trinity Church is a Russian Revival Orthodox church in Chelyabinsk, consecrated on 12 October 1914. It is the city's largest church, with an interior of rich Vasnetsov-style frescoes and a cedar iconostasis. The church holds relics of St Seraphim of Sarov, St Tryphon, St Andrew the First-Called, St Panteleimon and St Matrona of Moscow.

A first Holy Trinity church was founded in Zarechye in 1768. In 1909 the parish decided to replace it, construction began in 1911, and the new church was consecrated on 12 October 1914. Soviet authorities closed it on 1 October 1929, destroying its domes and bells and vandalising the interior; after a plan for a cinema, the regional museum moved in. The building was restored in 1987–1988 and returned to the Chelyabinsk eparchy in 1990.

The church keeps particles of relics of Seraphim of Sarov, Tryphon, Andrew the First-Called, Panteleimon and Matrona of Moscow. Its choir performs works by Rachmaninoff, Bortnyansky, Chesnokov and Tchaikovsky, and the interior frescoes follow the Vasnetsov style.

The church stands in the Zarechye district, on the far side of the Miass river from the city centre. Visitors enter through the main porch beneath the bell tower; the interior frescoes and cedar iconostasis are best seen outside service hours. Current service times and visiting conditions are posted on the parish website hram-troica74.ru.

The church keeps relics of Seraphim of Sarov, the Great Martyr Tryphon, the Apostle Andrew the First-Called, the healer Panteleimon and Blessed Matrona of Moscow. Its choir performs works by Rachmaninoff, Bortniansky, Chesnokov and Tchaikovsky. The Moscow Central Historical Archive replied to a Ural query that no documents about the church survive beyond an insurance valuation.