Nissay Sasashima Building, Office skyscraper in Nakamura district, Nagoya, Japan.

Nissay Sasashima Building is an office tower in Meieki-minami, Nakamura-ku, Nagoya, completed in 1974 by Nippon Life Insurance on a block bounded by Meitetsu Lejac, the Meitetsu Bus Center approach road and Meieki-dori. Its ground floor houses the Actus Nagoya interior shop, while upper floors are leased as offices.

The building was commissioned by Nippon Life Insurance Company in 1974 and designed and constructed by Takenaka Corporation. Its completion marked an important moment in the development of Nagoya's business district during a period of economic growth.

The ground floor holds the Actus Nagoya interior shop, a retail use unusual for an office block. Tenants have included Chubu Shiryo's head office, Fuji Soft, Denso Aitec's Nagoya head office and Kurimoto Steel Works. Nippon Life built the block in 1974 around the approaches to the Meitetsu Bus Center.

The building sits near three major train stations and offers easy access by public transportation from around the city. The central location makes it straightforward to reach from different parts of Nagoya.

Nippon Life built the tower in 1974 on a block enclosed by the Meitetsu Leisure Center, the Meitetsu Bus Center approach road and Meieki-dori. IBM once rented many floors and mounted its own sign on the facade; the sign came down after the company moved to other premises.