Hitsusa-jinja, Shinto shrine in Japan

Hitsusa-jinja is a Shinto shrine in the Jūzenji district of Hino, Shiga Prefecture. Its approach begins at a large pale-grey torii with cylindrical uprights, a curved lintel and a central plaque, hung with a straw rope and paper strips. The grounds include a hōkyōintō stone pagoda dated 1304 and subsidiary shrines to Amaterasu and Nogami.

Listed as a probable shrine of the Engishiki, Hitsusa-jinja served as the tutelary shrine of Hissa district. In the medieval period it became a shrine estate of Hiyoshi Shrine and, as one of the Hiyoshi Seven Shrines, received the Jūzen Gongen deity, being called "Hissatsu Jūzenji". Its hall was rebuilt in 1371, 1486, 1717 and 1808, burned in 1884 and rebuilt two years later; it was ranked village shrine in 1882, district shrine in 1926 and prefectural shrine in 1931.

The shrine's name is written 比都佐神社, read Hitsusa-jinja, and its crest is the mitsudomoe, three comma shapes in a circle. It was the sōsha, or tutelary shrine, of the former Hissa district, and in the medieval period it became one of the Hiyoshi Seven Shrines under Hiyoshi Taisha, when the Jūzen-gongen deity was invited here and the site was called Hissatsu Jūzenji. The annual festival is held on April 14.

The shrine stands in the Jūzenji district of Hino, Shiga Prefecture, and its annual festival is held on 14 April. A low dark stone footing anchors each upright of the torii at the top of the short stone stair, and a roofed notice board stands to the right of the gate. The grounds also hold a stone hōkyōintō pagoda dated by inscription to 2 December 1304.

In the shrine grounds stands a stone hōkyōintō pagoda inscribed with the date "2 December, 2nd year of Kagen (1304)", a National Important Cultural Property. The main hall burned down in 1884 and was rebuilt two years later, in 1886. Records in the shrine's own Gokan-uketori nikki list rebuildings in 1371, 1486, 1717 and 1808.