West Chester Downtown Historic District

West Chester Downtown Historic District spans 521 acres with 3,137 buildings built between 1789 and the 1930s, showing a variety of architectural styles from different periods. High Street and Market Street serve as the main corridors, lined with restaurants, shops, and civic buildings that shape daily activity.

In 1784, the downtown was established on a grid pattern with 32 parcels divided by Gay Street and High Street. By 1788, West Chester became the county seat, establishing its role as the regional center.

Multiple performance venues, galleries, and the Chester County History Center occupy historic buildings throughout the district, serving as cultural gathering places for residents and visitors. These institutions shape how the community uses and values the downtown area today.

Street parking and municipal garages provide parking options, while frequent bus connections make it easy to arrive and move around. Walking is the best way to explore the different streets and discover shops and restaurants along the way.

G. Raymond Rettew and Wyeth Laboratories produced the first mass-manufactured penicillin here in 1943 during World War II, a breakthrough that saved countless lives. This overlooked chapter of medical history happened on a downtown street that still looks much as it did then.

Location: West Chester

GPS coordinates: 39.96028,-75.60556

Latest update: December 14, 2025 12:21