Greenup Lock and Dam, Navigation facility on Ohio River in Greenup County, United States.

Greenup Lock and Dam is a navigation facility on the Ohio River that enables barge traffic and commercial shipping to move upstream and downstream. The installation includes multiple gates and chambers designed to raise and lower vessels through different water levels.

The structure was built by the United States Army Corps of Engineers from 1954 to 1962 as part of efforts to improve navigation on the Ohio River. Its completion marked an important step in modernizing commercial shipping routes in the region.

Greenup Lock and Dam is the eleventh lock and dam downstream of Pittsburgh, 341 miles (549 km) along the Ohio River. Its two chambers are sized for the river's working traffic: the main lock is 1,200 feet long and 110 feet wide (366 m × 34 m), while the auxiliary lock measures 600 by 110 feet (183 m × 34 m). Visitors can compare the two chambers and watch barges queue for the main lock.

The site is accessible from nearby roads and offers vantage points to observe the lock operations and water management in action. Visiting during daylight hours provides the best opportunity to watch barge traffic moving through the facility.

Greenup is the eleventh lock and dam downstream of Pittsburgh, 341 miles (549 km) along the Ohio River. Its two chambers differ in size: the main lock for commercial barge traffic is 1,200 feet long and 110 feet wide (366 m × 34 m), while the auxiliary lock measures 600 by 110 feet (183 m × 34 m).