Catedral Basílica de San Salvador de Jujuy, National historical monument in San Salvador de Jujuy, Argentina.

The Cathedral Basilica of the Holy Saviour stands on Belgrano and Sarmiento streets facing Plaza General Belgrano, the city's founding square. Begun in 1736 and consecrated between 1761 and 1765, it keeps the original central nave; later work added an arcaded side atrium on Belgrano, a bell tower over balustrades, and an Italianate facade. A side chapel, the Camarín de la Virgen del Rosario, holds stained glass and votive lamps.

The current building was constructed starting around 1736, after earlier structures on the same site had collapsed, and was completed around 1765. It was elevated to the rank of basilica by Pope Pius XII in 1946, formally raising its standing within the Church.

The cathedral faces the main plaza and serves as a gathering point for the city's daily life, with local people passing through or stopping to pray at any hour. Religious processions and celebrations regularly spill out from its doors onto the surrounding streets.

The building sits directly on the main plaza of San Salvador de Jujuy and is easy to reach on foot from anywhere in the city center. The interior is open during prayer times and services, and visitors are expected to dress modestly.

The cathedral holds the image of Our Lady of the Rosary of Río Blanco and Paypaya, carved around 1690. Manuel Belgrano named her Patroness of the Army of the North on 25 May 1812, the same day the flag was blessed. Pope Benedict XV's delegate crowned the image in 1920.