St James the Great, St Kilda East, Anglican church building in St Kilda East, Australia.

St James the Great is an Anglican church located on Inkerman Street in St Kilda East featuring a main nave, extended sanctuary, and a side chapel dedicated to the Virgin Mary. Decorative stained glass windows throughout the interior catch light and define the character of the worship spaces.

The parish was founded in 1914, carved out of All Saints' East St Kilda and St Mary's Caulfield. The first land lot on Inkerman Street was bought on 28 May 1913 for £879, and a second lot for the vicarage followed on 24 April 1914 for £500. Archbishop Lowther Clarke laid the foundation stone on 10 April 1915; the church was dedicated on 23 June 1915 and services began on 27 June 1915.

The parish has followed Anglo-Catholic liturgy and teaching since its beginnings in the chapel of St John's Theological College. Its patron saint was chosen because James and John, sons of Zebedee, were brothers, mirroring the link to St John's. Since the 1940s the surrounding municipality has become the heart of Melbourne's Haredi Jewish community.

The building sits at 435 Inkerman Street in St Kilda East and is straightforward to locate in the neighborhood. Visitors should check ahead if they want to attend services or tour the interior to confirm access during their planned visit.

The parish's patron saint was chosen to echo St John's College: James and John were brothers, the sons of Zebedee. The first incumbent, Garnet Eric Shaw, had worked in the pearling industry and held both a mate's and a master's mariner certificate before his ordination in 1911.