Iglesia de Santo Toribio, Colonial church in San Diego district, Cartagena de Indias, Colombia.

Iglesia de Santo Toribio is a Catholic church in the San Diego district of Cartagena de Indias, at the northwestern corner of Plaza Fernández de Madrid where Calle Curato meets Calle del Sargento Mayor. Construction began in 1666, making it the last church raised in the city during the colonial period. It was declared a national monument in 1995.

Construction began in 1666 under Bishop Antonio Sanz Lozano, marking the end of religious building in Cartagena's colonial era. The church was completed during a period when the city was fortifying its defenses and consolidating its role as a major port.

The church is named after Toribio de Mogrovejo, the Spanish-born Archbishop of Lima (1581–1606) canonised in 1726, whose cult spread through the Spanish colonies. It stands in the San Diego quarter, a short walk from the Plaza Fernández de Madrid, and remains an active parish church where Mass is still held.

The church is accessible daily to visitors and worshippers and can be reached at Calle 38 number 6-107 near the intersection with Calle Curato and Calle del Sargento Mayor. When planning a visit, keep in mind that it functions as an active parish church and visiting hours may vary depending on religious services.

A cannonball from Admiral Vernon's 1741 attack lodged in the church walls and pierced the roof during a service without injuring anyone. This physical evidence of the bombardment remains visible within the building's structure today.