Edificio Tlatelolco, Government building in Juarez Avenue, Mexico City, Mexico.

Edificio Tlatelolco is a 25-story office tower on Avenida Juárez in Mexico City's historic center, rising 120 meters with 50,000 m² of floor area and 5-meter floor-to-ceiling heights. Designed by Ricardo Legorreta Vilchis and his son Víctor Legorreta, it is built of reinforced concrete and glass, with 13 elevators and the highest heliport in the historic center.

Construction began in 2003 and finished in March 2005, designed by Ricardo Legorreta Vilchis and his son Víctor Legorreta, inspired by the 1966 Torre de Tlatelolco. The site had held a two-story public parking lot, and before the 1985 Mexico City earthquake, a group of twelve-story buildings. The Secretaría de Relaciones Exteriores moved in during 2006.

The building has housed Mexico's Ministry of Foreign Affairs since 2006, serving as a key site for the nation's diplomatic work. Its location in the historic center reflects the neighborhood's role as a seat of government authority.

The tower is located in a busy commercial area and is accessible by foot from several metro stations in the city center. Note that this is an active government building, so public access may be limited to exterior views.

The tower stands on 65 piles driven 55 metres deep to pass through the soft former lakebed of Texcoco. Its 45 seismic dampers let it ride out an 8.5-magnitude quake, and it came through the 19 September 2017 earthquake without major damage. The site previously held a two-storey public car park, and before 1985 a group of twelve-storey buildings.