Houston Main Building, Demolished skyscraper site in the Texas Medical Center, Houston, US

The Houston Main Building, formerly the Prudential Building, was an 18-story, 500,000-square-foot tower in the Texas Medical Center, designed by Kenneth Franzheim and built of limestone and steel. Its landscaped grounds held a swimming pool and tennis courts, and a 16-by-47-foot fresco by Peter Hurd hung in the lobby. It was demolished on January 8, 2012.

The building was completed in 1952 during a period when Houston was transforming rapidly into a major business hub. This construction was among the first wave of tall buildings that would reshape the city's appearance for decades to come.

The lobby held Peter Hurd's 16-by-47-foot fresco "The Future Belongs To Those Who Prepare For It," commissioned by Prudential and depicting West Texas farm life, with Hurd himself painted as a soil conservation agent. MD Anderson offered the mural free to anyone who would move it; in 2010 a benefactor from Artesia, New Mexico, agreed to take it for the town's public library.

The building no longer exists: it was demolished on January 8, 2012, so there is nothing to visit at the Texas Medical Center site. The 16-by-47-foot fresco by Peter Hurd, "The Future Belongs To Those Who Prepare For It," was removed in 2010 and given to the public library of Artesia, New Mexico, where it can be seen today.

The lobby held Peter Hurd's 16-by-47-foot fresco "The Future Belongs To Those Who Prepare For It," commissioned by Prudential and depicting West Texas farm life, with Hurd himself painted as a soil conservation agent. MD Anderson offered it free; in 2010 a benefactor from Artesia, New Mexico, took it for the town's public library.