Horace Wilkinson Bridge, Cantilever road bridge in Baton Rouge, United States.

The Horace Wilkinson Bridge is a steel cantilever truss carrying Interstate 10 across the Mississippi River between Port Allen in West Baton Rouge Parish and Baton Rouge in East Baton Rouge Parish. Its span measures 1,387 metres, with a main span of 376.7 metres and a total length of 4,313 metres including approaches. The roadway runs beneath the truss, which rises to a pointed peak near the centre and rests on massive grey concrete piers, each pierced by a rectangular opening.

The crossing opened on April 10, 1968, and took its name from three generations of the Wilkinson family who together served 54 years in the state legislature. Planning began in the early 1960s to handle growing traffic between both riverbanks.

Locals call it the New Bridge because it is the younger of Baton Rouge's two river crossings, opened in 1968 downstream of the Huey P. Long Bridge of 1940. The name was fixed by Act 206 of the Louisiana Legislature in 1968, honouring three Horace Wilkinsons, father, son and grandson, who together served 54 years in the state legislature.

The bridge has no shoulders along its entire length, so a single breakdown can block a lane. Eastbound traffic narrows to one through lane plus a Washington Street exit lane around a sharp curve, and vehicles from I-110 South may cross all lanes to reach that exit only 0.4 km away. Westbound congestion builds where the St. Ferdinand Street ramp merges and I-10 loses a lane at the LA 1 exit.

The span rises 53 metres above the Mississippi, the greatest clearance of any bridge on the river. The steel truss peaks near the centre-left before sloping to both ends, and the roadway runs beneath it between two concrete piers, each pierced by a rectangular opening.