Jackson Hole, Mountain valley in Teton County, United States.

Jackson Hole is a graben valley in Teton County, Wyoming, running 55 miles (89 km) long and 6 to 13 miles (10 to 21 km) wide between the Teton Range to the west and the Gros Ventre Range to the east. Its floor averages 6,800 ft (2,100 m), dropping to 6,350 ft (1,940 m) near the southern boundary of Grand Teton National Park, which occupies the northwestern part of the valley.

John Colter, a member of the Lewis and Clark Expedition, reached this area in the winter of 1807 and is considered the first European visitor to the valley. Fur trappers worked through the region in the following decades, and by the late 19th century the first permanent settlers arrived in the remote territory.

The name comes from trapper David Edward Jackson, though the town of Jackson was only named in 1893 by Margaret Simpson so eastern mail could be forwarded west. Each May, Old West Days brings residents, visitors and neighbouring Native Americans together for dances and parades; summer adds the Grand Teton Music Festival and mid-September the Jackson Hole Fall Arts Festival.

The region welcomes visitors year-round, with summer and winter as the most popular seasons. An airport within the valley offers connections to several major American cities and makes arrival much more convenient.

The national elk refuge at the edge of the valley shelters thousands of animals each winter. This concentration of deer during the cold months ranks among the largest gatherings of their kind on the North American continent.