Wyoming Highway 110, Scenic road in Crook County, Wyoming, United States

Wyoming Highway 110 is a short road in Crook County that leads to Devils Tower National Monument in eastern Wyoming. It connects the main entrance area to the monument grounds across less than 1 mile.

The road was first built in 1917 with an eight percent grade and a ford at the Belle Fourche River. A bridge followed in 1928, and in the 1930s Civilian Conservation Corps crews realigned it, improving grades and carefully hiding the old route with stockpiled trees and sod. It was listed on the National Register of Historic Places in 2000.

The road's 1930s realignment by Civilian Conservation Corps camp NM-1 (1935–1938) buried the old grade under stockpiled young trees and sod, a technique that helped the route earn its National Register listing as an example of close integration with the natural surroundings.

From Wyoming Highway 24 the signed WYO 110 runs about 0.59 mile west to the monument entrance; inside the boundary the two-lane asphalt road continues roughly 3 miles to the visitor parking area west of the tower. The route passes headquarters and the visitor center, so drivers can stop there before continuing. Grades were eased in the 1930s, but the road still climbs toward the tower.

The road's 1917 route had an eight percent grade and forded the Belle Fourche River; a bridge replaced the ford in 1928. In the 1930s Civilian Conservation Corps crews realigned the road and hid the old alignment with young trees and sod stockpiled during construction.