Sacro Cuore di Gesù a Villa Lante, Gothic Revival church in Trastevere, Rome, Italy.

Sacro Cuore di Gesù a Villa Lante is a church at Via San Francesco di Sales 18, inside the grounds of Villa Lante in Trastevere. Built in 1843 to Gerolamo Vantaggi's design, it is Rome's earliest Gothic Revival building, with pointed arches and Gothic detailing. Its interior holds works by painter Pietro Gagliardi (1809–1890).

Built in 1843 for the Society of the Sacred Heart of Jesus, founded by Saint Madeleine-Sophie Barat, the church was designed by Gerolamo Vantaggi, who took no fee and asked only for perpetual prayers and masses for his soul. It was the first church in Rome dedicated to the Sacred Heart and the city's first Gothic Revival building, a title sometimes wrongly given to Sant'Alfonso all'Esquilino (1855–59).

The church was built for the Society of the Sacred Heart of Jesus, founded by Saint Madeleine-Sophie Barat, and it still serves with the adjoining building as the order's provincial curia in Rome. Inside are works by Pietro Gagliardi (1809–1890). It is an annex church of the parish of Santa Dorotea.

The church is located in Trastevere at Via San Francesco di Sales 18 and is accessible on foot from central areas. Visitors should note it is an active place with regular religious activities.

The title of Rome's first Gothic Revival building is often wrongly given to Sant'Alfonso all'Esquilino, built in 1855–59 by the Scottish architect George Wigley, twelve years after Vantaggi's church. The interior holds works by Pietro Gagliardi (1809–1890).