Palazzo Budini Gattai, Renaissance palace in Piazza della Santissima Annunziata, Italy.

Palazzo Budini Gattai stands at via de' Servi 51, on the corner of Piazza Santissima Annunziata. Giuliano di Baccio d'Agnolo began it in 1563 and Bartolomeo Ammannati continued the work until 1574, completing the ground floor and the facade facing the piazza. The third storey was added between the 17th and 18th centuries, and in 1772 Pietro Grifoni had the piazza side finished to its present form.

The building was constructed during the 16th century as a result of collaboration between architects Giuliano di Baccio d'Agnolo and Bartolomeo Ammannati. Their combined work shaped the palace's structure and aesthetic during the height of Florentine Renaissance design.

The name recalls the Grifoni family, who bought the site in 1549; their crest was remade in the 1891-1892 works by Giuseppe Boccini. That renovation added the monumental two-ramp staircase and the painted decoration of the piano nobile, still cited as an example of Florentine upper-class taste around 1900. The palace also keeps a marble plaque with a winged Pegasus, marking the seat of Tuscany's first regional government in 1970.

The palace is centrally located near the Cathedral and easily reached on foot when visiting downtown Florence. Visitors should know that access to the interior depends on special events and the space is not typically open to the general public on a daily basis.

From March 2010 to April 2024 the piano nobile housed the photo library of the Kunsthistorisches Institut in Florenz. In the entrance hall a marble plaque of Monte Altissimo, topped by a winged horse, Pegasus, recalls that the first Tuscan regional government sat here from 1970. The Budini Gattai family still owns the palace and the adjoining Loggiato dei Servi di Maria, and lets the rooms for conferences and special events.