Palazzo Capilupi, Renaissance palazzo in Campo Marzio, Rome, Italy.

Palazzo Capilupi is a Renaissance palazzo on Via dei Prefetti with additional entrances on Vicolo Rosini and Vicolo Valdina. The structure displays typical Renaissance architectural features throughout its design and organization.

Bishop Ippolito Capilupi, representing Federico II Gonzaga and the Mantuan court at Charles V's coronation in 1534, bought the building from the Degli Stazii. Under him it was restored with advice said to include Michelangelo's, and it held a picture gallery moved to Mantua after his death.

The residence reflects the taste of Mantuan aristocracy through the art collection it once housed. Walking past the building gives a sense of what mattered to the regional nobility during the Renaissance.

A commemorative plaque at 17 Via dei Prefetti marks the location of a historical fountain that once depicted the Capitoline Wolf. Visitors can locate and read this marker to learn more about the site's past.

The inventor of the telegraph, Samuel Morse, lived in this palazzo from February 1830 to January 1831, as documented by a plaque on the facade. His stay connects the building to a pivotal moment in the history of telecommunications.