Sant'Ambrogio Church, Church building in Lierna, Lombardy, Italy

The church of Sant'Ambrogio di Lierna is a Catholic parish church in the town of Lierna, on the eastern shore of Lake Como in Lombardy. It has a plain stone facade, a tiled roof, and a Romanesque bell tower that rises above the surrounding rooftops.

The church's dedication to Saint Ambrose stems from the early medieval period, when Lierna belonged to the Milanese monks of San Dionigi and depended on the Archdiocese of Milan. Between the late 16th century and the first quarter of the 17th century, a campaign of works enlarged the building, ending with its reconsecration in 1627. A second enlargement followed in 1778.

The dedication to Saint Ambrose reflects Lierna's early medieval link to Milan: the area belonged to Milanese monks of San Dionigi and depended on the Archdiocese of Milan. Local oral tradition credits Ambrose with miracles, including an appearance on horseback with a drawn golden sword in the mountains around 1337.

The church stands in the hamlet of Villa, part of Lierna, on the eastern shore of Lake Como. The bell tower, dating to around the year 1000, is one of the oldest in Lombardy and can be picked out from the surrounding houses. The facade is Baroque in style, with the entrance portal and a three-lobed window above it holding an early-20th-century stained glass of Saint Ambrose.

The five frescoes on the vault were painted in the first decades of the 20th century by an artist of the Tagliaferri family, not in 1936. The bell tower dates to around the year 1000 and is among the oldest in Lombardy. Local legend holds that one of the nails of the Crucifixion was buried at Lierna.