Chiesa di San Paolo, Baroque basilica in Palazzolo Acreide, Italy.

Chiesa di San Paolo is a baroque church in the heart of Palazzolo Acreide, in Sicily, with a three-story facade adorned with Corinthian columns and twelve statues of the apostles along the top level. A central bell tower rises above the building and shapes the outline of the main square.

The original building was destroyed in the 1693 earthquake that leveled much of the town. The church seen today was built between 1720 and 1730 as part of the broader reconstruction of Palazzolo Acreide.

Paul was elected principal patron of Palazzolo Acreide by a popular assembly in September 1688, replacing the Virgin Odigitria; the Congregation of Rites confirmed the choice in July 1690. The church was the seat of one of the town's districts, and its community, the sampaolari, clashed with the rival sambastianari of San Sebastiano, a rivalry studied by the anthropologist Giuseppe Pitrè.

Access to the church is by a single flight of 11 steps from the street to the churchyard, where a three-arch portico stands; six more steps through the central arch lead to the vestibule. The side arches have stone balustrades, so the central opening is the only stepped route to the doors.

The central bell tower is topped with an onion-shaped dome, a form rarely seen in Sicilian baroque architecture. This shape is more commonly associated with Eastern European or Ottoman buildings than with churches in southern Italy.