San Defendente Church, Baroque church in Romano di Lombardia, Italy

San Defendente Church stands on Piazza Grande in Romano di Lombardia, linked by corridors and sacristies to the parish church and the Madonna di Lourdes church. Its interior has an incomplete Greek-cross plan with a barrel vault without tie rods, a main nave and a smaller left nave created by opening former chapels. The first chapel on the left holds Aurelio Gatti's Trittico del crocifisso in a wooden frame; the third has Enea Salmeggia's Trinità.

The church was authorized in 1490 and built from 1503 after the 1424 plague, when the community credited San Defendente with saving them. The deep raised presbytery with its grand staircase was added between 1642 and 1644 to the design of Romano-born Giovanni Antonio De Rossi, avoiding changes to the street behind. Elia Fornoni enlarged the church in the early 1900s, adding a new facade with a pronaos that incorporated the old marble portal.

The church serves as a focal point for the community where locals gather for religious ceremonies and celebrations throughout the year. It holds significance for those who practice their faith in Romano di Lombardia.

The church is located on Piazza San Defendente and welcomes visitors through its main entrance facing the square. Opening hours may vary depending on religious services and ceremonies being held.

The church was a meeting place for Romano's General Council of neighbours in the 16th and 17th centuries, while the square outside served for games and gatherings. A silver reliquary for the relics of Mary Magdalene, ordered in Venice by the merchant Bernardino Agazzi in 1621, carries both the town's coat of arms and the Agazzi family crest; it is kept on the altar of the Immaculate Conception, built by the same family in 1797.