Jizō-ji, Buddhist temple on the Shikoku pilgrimage route in Itano, Japan.

Jizō-ji is a Buddhist temple in Itano, Japan, made up of several buildings including a main hall, subsidiary halls, and a storehouse. The structures were built at different times and some are designated as cultural properties.

According to temple tradition, Kōbō Daishi founded Jizō-ji in 821, carving a small armoured Kōgun Jizō as its main image. A later monk, Jōkan, is said to have carved an 80 cm Enmei Jizō and placed the original image inside it. The complex once had 26 sub-temples and some 300 branch temples, but in 1582 Chōsokabe Motochika's troops burned it all; the Tokugawa-era Hachisuka lords of Tokushima helped rebuild it. The Hondō and Daishidō date from 1711–16, the Fudōdō from 1751–1830, the Kyōgura from 1810 and the Gohyakurakandō from 1922.

Jizō-ji is the fifth stop on the Shikoku pilgrimage route, one of the most followed sacred paths in Japan. Many visitors arrive dressed in white pilgrim robes and carrying a wooden staff, giving the site a visibly devotional character.

The temple lies in the Rakan district of Itano, about 3.4 km from JR Itano Station on the Kōtoku line, or 0.3 km from the Rakan bus stop on the Tokushima Bus Kajiyabara line. Drivers reach it from Itano IC (5 km) or Aizumi IC (6 km). Free parking holds 50 cars and 10 buses; there is no lodging.

The temple takes its name from Jizō, a bodhisattva figure widely venerated in Japan as a protector of travelers and children. This connection gives the site a personal meaning for many pilgrims who stop here during their journey.