United States Marine Hospital of Louisville

The United States Marine Hospital of Louisville is a former hospital near the Ohio River in Louisville, built in Greek Revival style. The structure features a three-story central block with symmetrical wings positioned on a hilltop overlooking the waterway.

Congress established the hospital in 1845 as part of a federal network of seven medical facilities to care for maritime workers. The Sisters of Mercy took over medical operations from 1869 to 1875, implementing organized patient care systems.

The building was designed specifically for river workers and sailors who needed medical care during their travels along the Ohio River. The presence of the Sisters of Mercy shaped how people understood this place as a site of care for working people.

The building is visible from the street and easy to locate, though it sits on elevated ground with steps leading to the entrance. Visitors should wear comfortable shoes and expect to find interior spaces preserved with historical details from the period.

It is the only surviving example of a pre-Civil War marine hospital from the federal healthcare initiative of the 1840s. The building showcases early technical innovations including specialized ventilation systems that helped reduce infection rates among patients of that era.

Location: Louisville

Inception: 1845

Address: 2215 Portland Avenue

GPS coordinates: 38.27100,-85.78398

Latest update: December 13, 2025 11:41