Izumi Inoue Shrine, Shinto shrine in Izumi, Osaka Prefecture, Japan.

Izumi Inoue Shrine is a Shinto shrine in Fuchu-cho, Izumi, Osaka Prefecture. Its main hall, rebuilt in 1895 in the taisha-zukuri style, stands beside a worship hall and the now-dry Izumi Shimizu spring, a designated historic site. Within the grounds also stands the Izumi Gosha Soja hall, rebuilt in 1605 by Toyotomi Hideyori with Katagiri Katsumoto as magistrate, in the sangensha nagare-zukuri style with a cypress-bark roof.

Tradition holds that a spring burst forth when Empress Jingu passed through in the 2nd year of Emperor Chuai (193), or again in the 9th year (200) on her way to Korea; the shrine was founded around this sacred water. In 716 the Izumi district was separated from Kawachi, and the provincial capital grew around the shrine. In 1605 Toyotomi Hideyori rebuilt the Gosha Sosha hall, demoting this shrine to a subordinate status until 1908.

The shrine's name comes from the Izumi清水 spring beside the main hall, held to be the origin of the name of Izumi Province. The autumn festival on 4–6 October features danjiri float processions; a 1585 record of six floats is the oldest danjiri record in the Senshu region. The Izumi Gosha Soja within the grounds honours the deities of five provincial shrines: Otori, Izumi Anashi, Hijiri, Tsugawa and Hine.

The shrine is a five-minute walk from JR Hanwa Line's Izumi-Fuchu Station. The grounds hold the main hall, the Gosha Sosha hall, subsidiary shrines, and the dry Izumi Shimizu spring. The former provincial government site is marked by a stone monument in Otachiyama Park just east of the shrine.

The sacred spring beside the main hall, called Izumi Shimizu, is said to have given Izumi Province its name; it is an Osaka Prefecture designated historic site. Toyotomi Hideyoshi had water drawn from it for tea while he was at Osaka Castle. The spring has now run dry.