Madame Tussauds San Francisco, Wax museum in Fisherman's Wharf, San Francisco, United States.

Madame Tussauds San Francisco was a wax museum located at Fisherman's Wharf that displayed lifelike figures of celebrities, politicians, athletes, and cultural icons. The exhibition was organized into themed sections showcasing different areas of public life and entertainment.

The museum opened in 2014 as the seventeenth location of the international wax museum brand founded by Marie Tussaud in London. It closed in 2024, with its collection distributed to other Madame Tussauds museums around the world.

A section titled "The Spirit of San Francisco" gathered wax figures of local artists, musicians and activists from the city's past. The rest of the collection covered film, music, politics, popular culture and sport. After the museum closed on 3 August 2024, most of the figures were sent to the 23 other Madame Tussauds sites worldwide.

Visitors could spend several hours walking through the different exhibition sections and taking photos with the figures. The Fisherman's Wharf location was easy to access and near other tourist attractions.

The 270-plus figures were not all shipped in: the site had housed the Wax Museum at Fisherman's Wharf for 50 years before Merlin Entertainments converted it in 2013. When Madame Tussauds closed on 3 August 2024, most of its figures went to the brand's 23 other locations worldwide.