Sigma Alpha Epsilon Fraternity House, Neo-Classical Revival fraternity house in Columbia, United States.

The Sigma Alpha Epsilon Building is a 2+1⁄2-story Neo-Classical Revival brick house with a T-shaped plan at 24 East Stewart Road on Oak Hill. Its front has a central pedimented portico carried by six two-story stone Ionic columns. Architect David Frederick Wallace, a fraternity brother, painted the dark brick white and added open side porches in the 1929 renovation.

The building was originally constructed in 1908 as a military academy before being remodeled in 1929 by architect Fred Wallace. Following fire damage, restoration work brought it back between 1965 and 1966, and the structure later earned recognition on the National Register of Historic Places.

Since 1986 the fall pledge class has turned the house into a haunted house each Halloween, drawing on legends of the basement, where dead soldiers' bodies were said to be stored when the building served as a Civil War hospital. A 1947 pledge class reportedly spent a night there and then left the university.

The building sits near the University of Missouri campus and is accessible from nearby streets. Since this is private residential property, visitors should view it from the exterior and respect the boundaries of the grounds.

The building underwent an unusual transformation from a military academy to a student fraternity across several decades. A fire in the 1960s prompted major restoration work that preserved its original architectural character.